Cover Image

An Improved Process for the Preparation of the p-tert-butylcalix[4]arene: from Laboratory-scale Synthesis to Scale-up Development

A. A. Fat'yanova, A. S. Gusak, O. A. Trofimova, P. E. Prokhorova

Abstract


The article describes the synthesis of p-tert-butylcalix[4]arene with different downloads of the starting compounds. The obtained data revealed the dependence of the yield on solvent, time and download amount. The description of technological process and material flows are given in this article.

Keywords


calix[4]arene; formalin; diphenyl ether; p-tert-butylphenol; condensation; efficiency; scalability; synthesis

Full Text:

PDF

References


Zadmard R, Tabar-Heydar K, Imani M. Separation of amino acids by high performance liquid chromatography based on calixarene-bonded stationary phases. J Chromatogr Sci. 2015;53(5):702–7. doi:10.1093/chromsci/bmu107

Casnati A. Calixarenes and cations: A time-lapse photography of the big-bang. Chem Commun. 2013; 49(61):6827–30. doi:10.1039/c3cc43165g

Atanassova M, Kurteva V. Synergism as a phenomenon in solvent extraction of 4f-elements with calixarenes. RSC Adv. 2016;6(14):11303–24. doi:10.1039/c5ra22306g

Afzal A, Iqbal N, Mujahid A, Schirhagl R. Advanced vapor recognition materials for selective and fast responsive surface acoustic wave sensors: A review. Anal Chim Acta. 2013;787:36–49. doi:10.1016/j.aca.2013.05.005

Gutsche CD. Calixarenes. London: Royal Society of Chemistry; 1989.

Sansone F, Baldini L, Casnati A, Ungaro R. Calixarenes: From biomimetic receptors to multivalent ligands for biomolecular recognition. New J Chem. 2010;34(12):2715–28. doi:10.1039/c0nj00285b

Montasser I, Shahgaldian P, Perret F, Coleman AW. Solid lipid nanoparticle-based calix[n]arenes and calix-resorcinarenes as building blocks: Synthesis, formulation and characterization. Int J Mol Sci. 2013;14(11):21899–942. doi:10.3390/ijms141121899

Gutsche CD, Dhawan B, No KH, Muthukrishnan R. Calixarenes. 4. The synthesis, characterization, and properties of the calixarenes from p-tert-butylphenol. J Am Chem Soc. 1981;103(13):3782–92. doi:10.1021/ja00403a028

Gutsche CD, Iqbal M, Stewart D. Calixarenes. 19. Synthesis procedures for p-tertbutylcalix[4]arene. J Org Chem. 1986;51(5):742–5. doi:10.1021/jo00355a033




DOI: https://doi.org/10.15826/chimtech.2016.3.2.010

Copyright (c) 2016 A. A. Fatyanova, A. S. Gusak, P. E. Prokhorova, O. A. Trofimova

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Scopus logo WorldCat logo DOAJ logo CAS logo BASE logo eLibrary logo

© Chimica Techno Acta, 2014–2024
ISSN 2411-1414 (Online)
This journal is licensed under a Creative Commons Attribution 4.0 International