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Technology for the industrial production of K3 series vitamins based on menadione

Aleksey S. Antipov, Vasily A. Nizov, Anna Yu. Antipova

Abstract


An improved technology for the industrial production of K3 series vitamins based on menadion is reported. The procedure involves the Cr(VI)-promoted oxidation of the corresponding methyl-naphtahelenes with the following purification by precipitation/recrystallization. The best results were obtained under the process temperature between 20-40 °C, solution pH after dilution of MNB in a range of 5.5–5.7, and MNB content in initial solution of 25-30%.

Keywords


Vitamin K3; methyl-naphalenes; Cr(VI)-compounds; menadione; industrial scale

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References


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DOI: https://doi.org/10.15826/chimtech.2020.7.2.05

Copyright (c) 2020 Aleksey S. Antipov, Vasily A. Nizov, Anna Yu. Antipova

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