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Features of -C-C- coupling of quinoxaline-2-one with ethyl acetoacetate under acid catalysis

Y. A. Azev, O. S. Koptyaeva, A. A. Mkrtchan, T. A. Pospelova

Abstract


Quinoxalin-2-one (1) reacts with ethyl acetoacetate in trifluoroacetic acid (TFA) to form 3-(2-oxopropylideno)-3,4-dihydroquinoxaline-2-one (2) and 3-(3-oxo-3,4- dihydroquinoxaline-2-(1H)-ylidene)methylquinoxaline-2-(1H)-one (3). The reaction product 3 was also obtained by heating the compound 1 with acetone in the presence of TFA.


Keywords


quinoxaline-2-one; ethyl acetoacetate; nucleophilic substitution of hydrogen; vicarious substitution; acid catalysis

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References


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DOI: https://doi.org/10.15826/chimtech.2022.9.1.03

Copyright (c) 2021 Y.A. Azev, O.S. Koptyaeva, A.A. Mkrtchan, T.A. Pospelova

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Chimica Techno Acta, 2014-2022
ISSN 2411-1414 (Online)