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Voltammetric sensor based on molecular imprinted polymer for lincomycin determination

Yulia A. Yarkaeva, Daria A. Dymova, Marat I. Nazyrov, Liana R. Zagitova, Valery N. Maistrenko

Abstract


For the selective detection of the antibiotic lincomycin, we developed a voltammetric sensor based on a glassy carbon electrode modified with reduced graphene oxide and polyarylenephthalide containing diphenylenethio and diphenyleneoxide fragments in the main chain of the polymer in the 1:1 ratio with lincomycin molecular imprints obtained by phase inversion. Using FTIR spectroscopy, electrochemical impedance spectroscopy, cyclic and differential-pulse voltammetry, the electrochemical and analytical characteristics of the sensor were studied. The detection of lincomycin was carried out by differential pulse voltammetry. The linear concentration range was 2.5·10–7–5·10–4 M with a limit of detection of 6.8·10–8 M. It was shown that the presence of molecular imprints increases the sensitivity of the developed sensor in comparisons with a sensor with non-imprinted polymer by a factor of 3.05.

Keywords


molecularly imprinted polymers; polyarylenephthalides; voltammetry; lincomycin; reduced graphene oxide; phase inversion

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References


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DOI: https://doi.org/10.15826/chimtech.2023.10.2.10

Copyright (c) 2023 Yulia A. Yarkaeva, Daria A. Dymova, Marat I. Nazyrov, Liana R. Zagitova, Valery N. Maistrenko

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