Ceramic materials based on lanthanum zirconate for the bone augmentation purposes: cytocompatibility in a cell culture model

Maria Ulitko; Yulia Antonets; Irina Antropova; Albert Mullabaev; Elena Volokitina; Anna Kasyanova; Ekaterina Loginova; Nataliia Tarasova

doi:10.15826/chimtech.2023.10.4.02

Ceramic materials based on lanthanum zirconate for the bone augmentation purposes: cytocompatibility in a cell culture model

Maria Ulitko, Yulia Antonets, Irina Antropova, Albert Mullabaev, Elena Volokitina, Anna Kasyanova, Ekaterina Loginova, Nataliia Tarasova

Abstract

Creation of new ceramic materials for the bone augmentation purposes that combine the absence of cytotoxicity, high strength and osseointegration characteristics is an urgent modern task. In this work, the cytocompatibility of ceramic materials based on lanthanum zirconate (La₂Zr₂O₇) was determined to assess the prospects for their use as implants and components of human joint endoprostheses. The effect of ceramic materials based on undoped and alkali-earth (Ca, Sr) doped La₂Zr₂O₇ on the viability and proliferative activity of human cells was evaluated. The release of elements into the culture medium was also evaluated.

Keywords

lanthanum zirconate; bioceramics; osteoreplacement material; cytocompatibility; cell culture

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DOI: https://doi.org/10.15826/chimtech.2023.10.4.02

Copyright (c) 2023 Maria Ulitko, Yulia Antonets, Irina Antropova, Albert Mullabaev, Elena Volokitina, Anna Kasyanova, Ekaterina Loginova, Nataliia Tarasova

This work is licensed under a Creative Commons Attribution 4.0 International License.

Chimica Techno Acta, 2014-2024
ISSN 2411-1414 (Online)
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