Email this article 
New spiro-heterocyclic coumarin derivatives as antibacterial agents: design, synthesis and molecular docking
Abstract
Keywords
Full Text:
PDFReferences
Rodriguez-Enriquez F, Costas- Lago C, Besada P, Alonso-Pena M, Torres-Teran I, Vina D, Teran C. Novel coumarin-pyridazine hybrids as selective MAO-B inhibitors for the Parkinson’s disease therapy. Bioorg Chem. 2020; 104:104203. doi:10.1016/j.bioorg.2020.104203
García-Beltrán O, Mena NP, Aguirre P, Barriga-Gonzalez G, Galdámez A, Nagles E, Núñez MT. Development of an iron-selective antioxidant probe with protective effects on neu-ronal function. J PloS one. 2017;12(12):0189043. doi:10.1371/journal.pone.0189043
Aguirre P, García-Beltrán O, Tapia V, Muñoz Y, Cassels BK, Núñez MT. Neuroprotective effect of a new 7, 8-dihydroxycoumarin-based Fe2+/Cu2+ chelator in cell and an-imal models of Parkinson’s disease. ACS Chem Neurosci. 2017;8(1):178-185. doi:10.1021/acschemneuro.6b00309
Al-Abbasy OY, Younus SA, Rashan AI, Ahmad OA. Maillard reaction: formation, advantage, disadvantage and control. A review. Food Sci Appl Biotech. 2024;7(1):145–161. doi:10.30721/fsab2024.v7. i1.333
Shen YF, Liu L, Feng CZ, Hu Y, Chen C, Wang GX, Zhu B. Synthesis and antiviral activity of a new coumarin deriva-tive against spring viremia of carp virus. Fish Shellfish Im-munol. 2018; 81:57-66. doi:10.1016/j.fsi.2018.07.005
Sahoo CR, Paidesetty SK, Sarathbabu S, Dehury B, Senthil Kumar N, Padhy RN. Molecular dynamics simulation, syn-thesis and topoisomerase inhibitory actions of vanillin de-rivatives: a systematic computational structural integu-ment. J Biomol Struct Dyn. 2022;40(22):11653-11663. doi:10.1080/07391102.2021.1961867
Cione E, La Torre C, Cannataro R, Caroleo MC, Plastina P, Gallelli L. Quercetin, epigallocatechin gallate, curcumin, and resveratrol: from dietary sources to human microRNA modulation. Molecules. 2019;25(1):63. doi:10.3390/molecules25010063
Ali OT, Mohammed MO, Al Dulayymi JR, Baird MS. Synthe-sis of a di-mycoloyl tri-arabinofuranosyl glycerol fragment of the mycobacterial cell wall, based on synthetic mycolic acids. Molecules. 2019;24(19):3596. doi:10.3390/molecules24193596
Galvin CJ, Hobson M, Meng JX, Ierokomos A, Ivanov IE, Ber-ger JM, Bryant Z. Single-molecule dynamics of DNA gyrase in evolutionarily distant bacteria Mycobacterium tuberculo-sis and Escherichia coli. Bio chem; 2023: 299(5). doi:10.1016/j.jbc.2023.103003
Khan T, Sankhe K, Suvarna V, Sherje A, Patel K, Dravyakar BDN. A gyrase inhibitors: Progress and synthesis of potent compounds as antibacterial agents. Biomed Pharmacother; 2018; 103: 923-938. doi:10.1016/j.biopha.2018.04.021
Maxwell A. DNA gyrase as a drug target. Trends Microbiol. 1997; 5:102–109. doi:10.1016/S0966-842X(96)10085-8
Rashan AI, Altaee RT, Salh FS, AL-Abbasy OY, Al-Lehebe N. The role of polyamines in plants: A review. Plant Sci Today. 2023; 10:164–171. doi:10.14719/pst.2520
Patil SA, Unki SN, Kulkarni AD, Naik VH, Badami PS. Co (II), Ni (II) and Cu (II) complexes with coumarin-8-yl Schiff-bases: spectroscopic, in vitro antimicrobial, DNA cleavage and fluorescence studies. Spectrochim Acta A Mol Biomol Spectrosc. 2011;79(5):1128-1136. doi:10.1016/j.saa.2011.04.032
Abdelmohsen SA, El-Emary T. Synthesis, characterization and antimicrobial activity of novel pyrazolo [3, 4-b] pyri-dines and their spiro-hetero cyclic derivatives. J Adv Chem. 2014;10(7). doi:10.24297/jac. v10i7.6802
Patagar D, Uttarkar A, Patra SM, Patil JH, Kusanur R, Niran-jan V, Kumar HA. Spiro benzodiazepine substituted fluo-rocoumarins as potent anti-anxiety agents. Russ J Bioorg Chem. 2021;47(2):390-398. doi:10.1134/S1068162021020199
Abd Allah OA, Elkhayat ES, Moustafa AH, Fahmy AA. Synthe-sis and Characterization of Some Novel Indole-2-One-Coumarin Hybrids. Sohag J Sci. 2024;9(2):186-189. doi:10.21608/sjsci.2024.248555.1148
Özer H, Sökmen M, Güllüce M, Adigüzel A, Şahin F, Sökmen A, Bariş Ö. Chemical composition and antimicrobial and an-tioxidant activities of the essential oil and methanol extract of Hippomarathrum microcarpum (Bieb.) from Turkey. J Agric Food. 2007;55(3):937-942. doi:10.1021/jf0624244
Vashistha VK, Mittal A, Bala R, DASa DK, Singh PP. Synthe-sis, characterization, electrochemical and antibacterial studies of mn4-type macrocyclic complexes of Ni (II). Rev Roum Chim. 2023;68(9):447-452. doi:10.33224/rrch.2023.68.9.05
Almaghrabi M, Musa A, Aljohani AK, Ahmed HE, Alsulaim-any M, Miski SF, El-Agrody AM. Introducing of novel class of pyrano [2, 3-c] pyrazole-5-carbonitrile analogs with potent antimicrobial activity, DNA gyrase inhibition, and promi-nent pharmacokinetic and CNS toxicity profiles supported by molecular dynamic simulation. ACS Omega. 2023;8(20):17948–17965. doi:10.1080/07391102.2023.2252088
Rodriguez SV, Guíñez RF, Matos MJ, Azar CO, Maya JD, San-tana L, Borges F. Synthesis and trypanocidal properties of new coumarin-chalcone derivatives. Med Chem. 2015;(5):173-177. doi:10.4172/2161-0444.1000260
Ahmed EY, Abdelhafez OM, Zaafar D, Serry AM, Ahmed YH, El‐Telbany RFA, Ali HI. Antitumor and multikinase inhibi-tion activities of some synthesized coumarin and benzofu-ran derivatives. Archiv der Pharmazie. 2022;355(6):2100327. doi:10.1002/ardp.202100327
Dar PA, Bhat BA, Mir MA, Chaudhari SY, Shah WA. Synthe-sis, biological profile and computational insights of new de-rivatives of benzo [B][1, 4] diazepines as prospective anti-cancer agents for inhibiting the CDK-2 protein. J Biomol Struct Dyn. 2024:1-16. doi:10.1080/07391102.2024.2314270
Solankee A, Tailor R. Synthesis, characterization and biolog-ical screening of s-triazine based chalcones and its derivati-zation into phenyl pyrazolines, isoxazoles. Int Lett Chem Phys Astron. 2015; 47:109-119. doi:10.56431/p-jy3j82
DOI: https://doi.org/10.15826/chimtech.2024.11.3.08
Copyright (c) 2024 Abdallah F. Al-burgus, Omar T. Ali, Omar Y. Al-abbasy
This work is licensed under a Creative Commons Attribution 4.0 International License.
© Chimica Techno Acta, 2014–2024
ISSN 2411-1414 (Online)
This journal is licensed under a Creative Commons Attribution 4.0 International