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New molecular complex of ammonium gycyrrhizate with rutin

L. A. Yakovishin, V. D. Ratnikov, P. I. Bazhan, G. P. Zaitsev

Abstract


A new 1:1 molecular complex of triterpene glycoside ammonium glycyrrhizate (GC) with flavonoid glycoside rutin (Rut) was obtained in aqueous ethanol. The stability constant (9.7±0.2)×104 (mol/L)–1 was calculated for the complex via isomolar curves. The complexation was studied by UV- and ATR IR-Fourier spectroscopy and a method of isomolar series. The hydrogen bonds and hydrophobic interactions are formed in the molecular complex. A preliminary antioxidant activity assessment of the complex was made.

Keywords


triterpene glycosides; ammonium glycyrrhizate; rutin; molecular complex; antioxidant capacity

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References


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DOI: https://doi.org/10.15826/chimtech.2022.9.1.01

Copyright (c) 2022 L.A. Yakovishin, V.D. Ratnikov, P.I. Bazhan, G.P. Zaitsev

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Chimica Techno Acta, 2014-2021
ISSN 2411-1414 (Online)